Research

Health Promotion and Disease Prevention Research Centers: 2025 Special Interest Project Competitive Supplements (SIPS)

Limit: 1 per SIP

K. Ellingson (Public Health) for SIP25-005 Understanding the potential of early childcare and education (ECE) centers in promoting childhood vaccines and RSV prevention products

S. Carvajal (College of Public Health's Prevention Research Center) for SIP25-006 Overdose Prevention and Treatment Research Network (OPTRN)

Eligibility: 
Only one application per SIP per institution is allowed (e.g., multiple applications for the same SIP (listed in Section VIII) from the same institution are NOT permitted).

Purpose:
This Notice of Funding Opportunity (NOFO) invites applications from CDC Health Promotion and Disease Prevention Research Centers (PRCs), selected for funding under RFA-DP-24-004, to apply for supplemental funding to conduct Special Interest Research Projects (SIPs) to inform public health practice. PRCs will conduct high-quality applied health promotion and disease prevention research projects in real-world settings to identify, design, test, evaluate, disseminate, and translate interventions (i.e., programs, practices, policies, or strategies) to prevent and reduce risk for the leading causes of illness, disability, and death in the United States.

Funding Type
Internal Deadline
External Deadline
2/28/2025

NIH PAR-23-077: Collaborative Program Grant for Multidisciplinary Teams (RM1 - Clinical Trial Optional) - May 2025 Deadline

Request Ticket // Limit: 2 // Tickets Available: 2

Number of Applications
The NIH will not accept duplicate or highly overlapping applications under review at the same time, per 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:

  • A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.
  • A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.
  • An application that has substantial overlap with another application pending appeal of initial peer review (see 2.3.9.4 Similar, Essentially Identical, or Identical Applications).

Two applications per institution (with a Unique Entity Identifier ) and a unique NIH eRA Institutional Profile File (IPF) number) are allowed per review round. The same or a similar topic may be submitted for subsequent review rounds involving the same or a similar team, but must be presented as a New application, not a Resubmission.

Applications that are not considered to be within the NIGMS mission will not be reviewed. Eligibility and appropriateness to the NIGMS mission will be evaluated again after review and prior to funding. Applications outside the NIGMS mission will not be funded. Given that only two applications are permitted per institution per review round, it is important to contact NIGMS staff before committing to any particular team and its topic area.

Purpose: 
This Funding Opportunity Announcement (FOA) is designed to support highly integrated research teams of three to six Program Directors/Principal Investigators (PDs/PIs) to address ambitious and challenging research questions that are within the mission of NIGMS. Project goals should not be achievable with a collection of individual efforts or projects. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

This FOA is not intended for applications that are mainly focused on the creation, expansion, and/or maintenance of community resources, creation of new technologies, or infrastructure development.

Funding Type
Internal Deadline
External Deadline
5/28/2025
Solicitation Type

NSF 25-521: Materials Innovation Platforms (MIP)

Limit: 1 // Tickets Available: 0
Q. Hao (Aerospace & Mechanical Engineering) 

Eligibility 
One (1) per organization as lead institution.

The institutions that were awarded a MIP in the 2019 competition as the lead institution are not eligible to submit a MIP proposal as a lead institution in the 2025 competition.

Synopsis
Materials Innovation Platforms (MIP) is a mid-scale infrastructure program in the Division of Materials Research (DMR) designed to accelerate advances in materials research. MIPs respond to the increasing complexity of materials research that requires close collaboration of interdisciplinary and transdisciplinary teams and access to cutting edge tools. These tools in a user facility benefit both a user program and in-house research, which focus on addressing grand challenges of fundamental science and meet national needs. MIPs embrace the paradigm set forth by the Materials Genome Initiative (MGI), which strives to “discover, manufacture, and deploy advanced materials twice as fast, at a fraction of the cost,” and conduct research through iterative “closed-loop” efforts among the areas of materials synthesis/processing, materials characterization, and theory/modeling/simulation. In addition, they are expected to engage the emerging field of data science in materials research. Each MIP is a scientific ecosystem, which includes in-house research scientists, external users and other scientists who, collectively, form a community of practitioners and share tools, codes, samples, data and know-how. The knowledge sharing is designed to strengthen collaborations among scientists and enable them to work in new ways, fostering new modalities of research and training, for the purpose of accelerating discovery and development of new materials and novel materials phenomena/properties, as well as fostering their eventual deployment.

The scientific focus of the MIP program is subject to change from competition to competition. Information about the existing MIPs, from two previous competitions in 2015 and 2019, can be found at mip.org. The third MIP competition, in 2025, will accept proposals on alloys, amorphous, and composite materials. Given that the second MIP competition included an emphasis on biomaterials and polymer research, proposals mainly on these topics will not be considered in the third MIP competition.

Funding Type
Internal Deadline
External Deadline
5/15/2025
Solicitation Type

Agricultural Genome to Phenome Initiative (USDA-NIFA-OP-011214)

RFA Withdrawn // Limit: 1 // Tickets Available: 1 

Duplicate or Multiple Submissions – submission of duplicate or predominantly overlapping applications is not allowed. NIFA will disqualify both applications if an applicant submits multiple applications that are duplicative or substantially overlapping to NIFA programs within the same RFA fiscal year. 

The National Institute of Food and Agriculture’s Agricultural Genome to Phenome Initiative (AG2PI), Assistance Listing 10.332, is intended to:  
1. Study agriculturally significant crops and animals in production environments to achieve sustainable and secure agricultural production. 
2. Ensure that current gaps in existing knowledge of agricultural crop and animal genetics and phenomics are filled. 
3. Identify and develop a functional understanding of relevant genes from animals and agronomically relevant genes from crops that are of importance to the agriculture sector of the United States. 
4. Ensure future genetic improvement of crops and animals of importance to the agriculture sector of the United States. 
5. Study the relevance of diverse germplasm as a source of unique genes that may be of importance in the future. 
6. Enhance genetics to reduce the economic impact of pathogens on crops and animals of importance to the agriculture sector of the United States. 
7. Disseminate findings to relevant audiences.  

Research in Basic Plasma Science and Engineering (DE-FOA-0003503)

Limit: 2 // Tickets Available: 0

M. Phillips (Optical Sciences)
B. Parent (Aerospace and Mechanical Engineering)

Executive Summary
The FES Discovery Plasma Science: Plasma Science and Technology–General Plasma Science (GPS) program seeks new or renewal single-investigator or small-group applications to carry out hypothesis-driven frontier-level research in basic plasma science and engineering. This program aims to develop accurate descriptions of the complex behavior of the plasma state, to push it into new regimes that expand our concept of what constitutes a plasma, to design experiments and diagnostics to explore these states, and to validate theoretical models. 

For more information, see GPS program science drivers in the CPP Report: A Community Plan for Fusion Energy and
Discover Plasma Sciences, 2019-2020. This NOFO is focused on fundamental research involving plasma including astrophysical, dusty, and low temperature plasmas. Research toward developing plasma-based technologies is out of scope of this NOFO.

Limitations on Submissions 
Applicant institutions are limited to no more than two pre-applications (or lead applications), and PIs may only be named on no more than one pre-application (or lead application).

Individuals named as DOE/NNSA National Laboratory PIs, Co-PIs, or senior/key personnel must be an indispensable part of the laboratory with their effort closely integrated into the laboratory’s current plasma science research program and supported at least 50% of their time by the laboratory.

If a multi-institutional team is submitting collaborative applications, only the lead institution should submit a pre-application that should include all institutions, institutional Co-PIs, and all other personnel and relevant information.

DOE will consider the latest received submissions to be the institution’s intended submissions.
• Pre-applications in excess of the limited number of submissions will be discouraged.
• Applications in excess of the limited number of submissions will be declined without review.

Funding Type
Internal Deadline
External Deadline
2/14/2025 (Required Pre-Application)

2025 Packard Fellowships for Science and Engineering

Limit: 2 // Available: 0
Y. Bai (Optical Sciences)
S. Kong (Astronomy) 
 

Eligibility: 

Must be a faculty members in the first three years of their faculty careers, that is, whose initial faculty appointments began no earlier than May 31, 2022, and no later than May 31, 2025.
 

The  Packard Fellowships for Science and Engineering Program invests in future leaders who have the freedom to take risks, explore new frontiers in their fields of study, and follow uncharted paths that may lead to groundbreaking discoveries.

Candidates must be faculty members who are eligible to serve as principal investigators engaged in research in the natural and physical sciences or engineering and must be within the first three years of their faculty careers. Disciplines that will be considered include physics, chemistry, mathematics, biology, astronomy, computer science, earth science, ocean science, and all branches of engineering. Candidates engaged in research in the social sciences will not be considered. 

The Fellowship Program provides support for highly creative researchers early in their careers; faculty members who are well-established and well-funded are less likely to receive the award.  Packard Fellows are inquisitive, passionate scientists and engineers who take a creative approach to their research, dare to think big, and follow new ideas wherever they lead.  

The Foundation emphasizes support for innovative individual research that involves the Fellows, their students, and junior colleagues, rather than extensions or components of large-scale, ongoing research programs.  
 

Funding Type
Internal Deadline
External Deadline
3/15/2025 (Nomination), 4/20/2025 (Proposal)

2025 Damon Runyon Clinical Investigator Award

No Applicants // Limit: 5 // Tickets Available: 5


The University of Arizona Cancer Center (UACC) can nominate five applications for the Damon Runyon Clinical Investigator Award

For more information please contact: UACC-PreAward.

Purpose of Award 

The Damon Runyon Clinical Investigator Award supports independent young physician-scientists conducting disease-oriented research that demonstrates a high level of innovation and creativity. The goal is to support the best young physician-scientists doing work aimed at improving the practice of cancer medicine.

The Clinical Investigator Award responds to three recognized realities:

  • Though there has never been a more pressing need or more promising time for clinical cancer research, fewer young physicians enter this area of investigation every year.
  • The number of institutions committed to training young physicians in the scientific discipline and methodologies of clinical investigation is critically low.
  • The burden of medical school debt (averaging over $100,000) discourages many physicians from pursuing clinical investigation.

The Damon Runyon Cancer Research Foundation’s award offers solutions to these realities. The awardee will receive financial support for three years, as well as assistance with certain research costs such as the purchase of equipment. The Foundation will also retire up to $100,000 of any medical school debt still owed by the awardee.

The Clinical Investigator Award program is specifically intended to provide outstanding young physicians with the resources and training structure essential to becoming successful clinical investigators. The goal is to increase the number of physicians capable of moving seamlessly between the laboratory and the patient’s bedside in search of breakthrough treatments.

 

Eligibility

  • The applicant must hold an independent Assistant Professor position or equivalent at a U.S. institution and is expected to demonstrate significant support from the home institution through a comprehensive start-up package, ample laboratory space, and protected research time, for example.
  • The applicant must have received an MD, DO, or MD/PhD degree(s) from an accredited institution, completed their subspecialty training and be U.S. Board eligible.
  • The applicant must hold a valid, active U.S. medical license at the time of application.
  • The applicant must apply within the first five (5) years of their Assistant Professor or equivalent full faculty appointment (Cut-off date: July 1, 2020). Instructor, Adjunct and/or acting positions are not eligible.
  • Candidates holding or awarded R01s (or R01-equivalent grants such as the DP2 and DP5) at the time of application are not eligible to apply.
  • The applicant must commit to spending 80% of their time conducting research. [In rare unique circumstances, the CIA Committee may consider an applicant with a very modest reduction of 80% protected time if their Department Chair can provide a compelling reason explaining why a waiver of the 80% requirement should be granted, what percentage of effort will be guaranteed, and what safeguards will be put in place to make sure the individual’s research will not be compromised by their clinical/administrative activities.]
  • The applicant is required to apply in conjunction with a Mentor who is established in the field of clinical translational cancer research, cancer prevention and/or epidemiology and can provide the critical guidance needed during the period of the award. No more than two Damon Runyon Clinical Investigators will be funded to work with the same Mentor at any given time (including Co-Mentors).
  • Candidates may apply up to two times during this eligibility period.
  • Only one application will be accepted from a Mentor per review session (including Co-Mentors).
Funding Type
Internal Deadline
External Deadline
2/3/2025

U.S. Nuclear Regulatory Commission Research and Development Grant, Fiscal (FY) 2025

Tickets: 3 // Tickets Available: 2

T. Bheemasetti (Civil Arch Engr and Mechanics) 

Executive Summary
The U.S. Nuclear Regulatory Commission (NRC) is an independent agency, established by the Atomic Energy Act of 1954, as amended, tasked with licensing, and regulating the Nation’s civilian use of byproduct, source, and special nuclear material to ensure adequate protection of public health and safety, to promote the common defense and security, and to protect the environment.

The program provides funding to support research and development (R&D) for nuclear science, engineering, technology, and related disciplines to develop a workforce capable of supporting the design, construction, operation, and regulation of nuclear facilities and the safe handling of nuclear materials. University R&D activities provide an opportunity to complement current, ongoing NRC-led research. More specifically, the program shall be used to provide financial assistance for R&D projects relevant to the programmatic mission of the NRC referenced above, with an emphasis on providing federal financial assistance with respect to research, development, demonstration, and commercial application of new and advanced nuclear technologies. Social science research will be considered under this announcement (for example, projects that would foster the development of innovative community engagement strategies, including incorporation of principles of equity and environmental justice).

The NRC invites R&D projects that complement its current research portfolio and that help the NRC prepare for upcoming challenges. A summary of NRC research activities can be found at NRC Research Activities in the FY22-24 Research Prospectus. The NRC seeks projects that provide a variety of direct and indirect, near- and long-term outcomes. These outcomes include:
 

  • Identification and closure of potentially important technical gaps ahead of
    regulatory needs,
  • Heightened awareness and knowledge of key advanced technology
    developments being pursued outside of NRC, and
  • Improved foundational knowledge on key topics of future regulatory interest.
     

Number of Applications

An institution may submit no more than three (3) applications in response to this
announcement.
 

Although the Primary Investigator (PI)s prepare the grant application and are responsible for conducting and supervising the research, the actual applicant is the educational institution. The same PIs may not be on more than one application. A PI may not be a Co-PI on another application in response to this announcement.
 

An application in response to this announcement may include more than one Co-PI. However, an individual can only be proposed as a Co-PI within one (1) application in response to this announcement.

Funding Type
Internal Deadline
External Deadline
1/31/2025
Solicitation Type

NAT-RD-24-0003 PFAS Reduction and Innovation in Semiconductor Manufacturing (PRISM) Call for Proposals (CFP)

Limit: 2* // Tickets Available: 0

Wastewater Focus Area - Limit: 1 // Tickets Available: 0
S. Savagatrup (Chemical and Environmental Engineering)

Air Focus Area - Limit: 1 // Tickets Available: 0
M. Phillips (Wyant College of Optical Sciences) 

The submission for this funding program is coordinated by the Center for Semiconductor Manufacturing.Please contact Dan Moseke, Project Director, for more information.

Limit: 
An organization may only lead up to two proposals maximum (one for each Focus Area - air and wastewater) but may participate on more than one team. 
 

Concise Description of Funding Opportunity: 
NSTC’s PRISM program aims to enhance the sustainability of semiconductor manufacturing by addressing the challenges posed by per- and polyfluoroalkyl substances (PFAS) usage. The objective of the PRISM program is the successful creation of end-to-end PFAS mitigation capabilities, integrating advanced analytical methods, abatement technologies, and predictive modeling to address the environmental impact of PFAS usage in semiconductor manufacturing. 

Funding Type
Internal Deadline
External Deadline
12/04/2024 (concept paper)

CMI-1-2024: Critical Materials Innovation Hub

Limit: 1 // Tickets Available: 0

S. Ndlovu (Mining and Geological Engineering) 

Limited Submission Eligibility
Lead Organizations are limited to one submission. No limits on partnering as sub-recipients.

Purpose and Objectives
The intent of this Request for Proposals (RFP) is to seek out new opportunities to accelerate the transformational advances in science and engineering necessary to reduce material criticality for energy innovation, with specific emphasis on industrial relevance, participation, and adoption. Additionally, CMI seeks projects that strengthen and expand its R&D portfolio by developing the capabilities and expertise across supply chain stages of materials contained in CMI materials scope. The current materials scope within CMI is summarized as shown in Table 1. It specifies whether the initial Phase III research efforts are directed toward process innovation, material innovation, or a combination of both. CMI materials scope includes magnetic rare earth elements, energy storage materials, platinum group metals, and gallium, germanium and tellurium. The current R&D profile reflects CMI’s strategic plan and vision (as informed by CMI Phase III Roadmap) to address challenges across four broadly defined parts of the supply chain: upstream, midstream, downstream, and materials innovation.
 

Cost Share Requirement
Cost share (20% minimum) required for matching federal support of private sector industrial team members. A minimum of 20% cost share of total project costs is encouraged. 

Funding Type
Internal Deadline
External Deadline
12/20/2024