Completed

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Only one application per institution is allowed.

The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) was amended by the Small Business Liability Relief and Brownfields Revitalization Act in 2002 to include Section 104(k), which provides federal financial assistance authorities for brownfields revitalization, including grants for assessment, cleanup, and revolving loan funds. The Brownfields Utilization, Investment, and Local Development (BUILD) Act (Public Law 115- 141) enacted in 2018 reauthorized EPA’s Brownfields Program and made additional amendments to CERCLA that affect EPA’s brownfield grant authorities, and ownership and liability provisions. (Note: References to CERCLA in this solicitation refer to CERCLA as amended by the 2002 Small Business Liability Relief and Brownfields Revitalization Act and the 2018 BUILD Act.) EPA’s Brownfields Program provides funds to empower states, Tribal Nations, communities, and nonprofit organizations to prevent, inventory, assess, clean up, and reuse brownfield sites. This guidance provides information on applying for Multipurpose Grants.

A Multipurpose (MP) Grant is appropriate for communities that have identified, through community engagement efforts, a discrete area (such as a neighborhood, a number of neighboring towns, a district, a corridor, a shared planning area or a census tract) with one or more brownfield sites. The target area may not include communities that are located in distinctly different geographic areas. 

Multipurpose Grant funds provide funding for communities to carry out a range of eligible assessment and cleanup activities, including planning and additional community engagement activities. The performance period for these grants is up to five years.

An applicant can apply for up to $1,000,000 and should demonstrate how grant funds will result in at least:

• one Phase II environmental site assessment;
• one brownfield site cleanup; and
• an overall plan for revitalization that includes a feasible reuse strategy for one or more brownfield sites, if there is not already a plan in place.

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Institutions may submit up to two applications under this Funding Opportunity so long as each one describes working with a distinct beneficiary community. 

The U.S. Environmental Protection Agency (EPA) is seeking applications for cooperative agreements to support the data, reporting, and evidence-building capacity of program beneficiaries, which include, recipients of grant funding from EPA as direct recipients of EPA funding and subrecipients who can participate in the Clean Water and Safe Drinking Water programs, particularly for those representing small, underserved, and/or tribal communities that are applying for or receiving EPA grant funding, including but not limited to funding under the Infrastructure Investment and Jobs Act (IIJA), Public Law 117-58 [also known as the Bipartisan Infrastructure Law (BIL)] funding and the Inflation Reduction Act (IRA), Public Law 117-169.

Applicants should describe how they would collaborate with other EPA funded technical assistance providers (e.g., Environmental Justice Thriving Communities Technical Assistance Centers, EPA Environmental Finance Centers and Technical Assistance for Brownfields recipients) to avoid duplication of effort and share best practices. Additionally, as provided in EPA’s General Terms and Conditions “Copyrighted Material and Data” (a link to which can be found in Section VI.w of EPA Solicitation Clauses), EPA may authorize the successful applicant to use copyrighted works or other data developed with Agency funds by other Federally funded technical assistance providers, or to require that the successful applicant allow other Federally funded technical assistance providers to use works or data developed with EPA funds, when such use promotes efficient and effective use of Federal grant funds.

EPA expects to make between 4 to 8 incrementally funded awards with periods of performance of up to three years with total funding of approximately up to $500,000 per award depending on funding availability, the quality of applications, satisfactory progress, and other applicable considerations. The specific number of awards and the amounts may vary from these estimates. The awards for selected projects will be in the form of cooperative agreements as it is expected that there will be substantial involvement and interaction between the applicant and EPA. The total estimated funding for this competitive opportunity is approximately $4 million.

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An organization may only submit 1 proposal as the lead. There is no limit on the number of proposals on which an organization can be included as a sub-recipient.

The National Science Foundation (NSF) is soliciting proposals for managing the operation and maintenance of the National Geophysical Facility (hereafter referred to as NGF) an NSF-funded major facility. The NGF is designed to enable the research community to ask, and address, questions about a variety of Earth processes from local to global scales. NGF will operate global and regional networks of sensors; provide a lending library of instrumentation and support services to enable PI-led field experiments; support archiving, quality control, and delivery of geophysical data and data product development; and provide education, outreach, workforce development, and community engagement activities that serve a wide range of audiences. NGF will be a single facility, with a single operator that will succeed NSF’s current geophysical facilities, the Seismological Facility for the Advancement of GEoscience (SAGE) and the Geodetic Facility for the Advancement of GEoscience (GAGE).

The award recipient will work closely with NSF and the scientific community to ensure that NGF capabilities support, and advance, Earth Sciences and related disciplines. In cooperation with NSF, and within available resources, the recipient will plan and execute a viable, coherent, and inclusive program to: (1) streamline the management and operations of existing geophysical facility capabilities into one consolidated geophysical facility; (2) enhance existing facility capabilities in instrumentation, data services and cyberinfrastructure; and (3) implement a bold vision to broaden participation and foster a culture of equity and inclusion in the Earth Sciences and related disciplines.

The NSF Division of Earth Sciences (EAR) in the Directorate for Geosciences (GEO) has primary responsibility for the programmatic oversight of NGF and activities will be coordinated with the Division of Ocean Sciences (OCE), Division of Atmospheric and Geospace Sciences (AGS), and Office of Polar Programs (OPP). 

A single award will be made as a cooperative agreement with a duration of five years. NSF may renew the award for an additional five years, subject to availability of funds, the recipient's satisfactory performance, and review of a cost proposal for the second 5-year period. NSF’s decision will be informed by the National Science Board Statement on Recompetition of Major Facilities (NSB 2015-45 or its successor).
 

For planning purposes, proposers can assume a base budget of approximately $39.5 million during the first year of the award, beginning October 2025 and should plan for no more than a 6% budget increase in each of the subsequent years. All budget amounts given herein are tentative and for initial planning purposes only. Actual annual funding increments will be determined based on the detailed cost estimate required per Section VII.C below and an Annual Plan and Budget submitted by the recipient to, and approved by, NSF. Funding increments are subject annually to the availability of funds and will be contingent on the performance of the recipient. Ongoing recapitalization of instrumentation, and escalation factors used for cost estimating, should be articulated in the Cost Estimating Plan.

Transition funding of up to $1,000,000 for a duration of up to six (6) months will be available for organizations other than the incumbent organization. Relevant transition activities include interviewing and hiring personnel, establishing subcontracts, transferring data and property, and obtaining permits and licenses. Should a transition period be necessary, the incumbent will retain responsibility for management of NGF and the new recipient will have the appropriate level of access to incumbent personnel and facilities associated with NGF as determined by NSF. The funding request for a transition period should be made within the Transition Plan and should not be included in the formal cost estimate or proposed budget for the initial 5-year period but must conform to the same requirements.

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An entity may submit only one Concept Paper and one Full Application to this FOA.

The research and development (R&D) activities to be funded under this FOA will support the government-wide approach to the climate crisis by driving the innovation that can lead to the deployment of clean energy technologies, which are critical for climate protection. Specifically, this FOA will invest in R&D to support continued innovation and cost reduction for high-voltage direct current (HVDC) voltage-source converter (VSC) transmission systems. This investment is intended to enable future grid upgrades required to integrate increasing renewable energy generation on to the grid, both onshore and offshore.EERE expects to make a total of approximately $10M of federal funding available for new awards under this FOA, subject to the availability of appropriated funds. EERE anticipates making approximately 3-4 awards under this FOA. EERE may issue one, multiple, or no awards. Individual awards may vary between $2.5M and $3.3M

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Only one application per institution is allowed.

The purpose of the “Clinical Trial Methods in Neurological Disorders Course" Notice of Funding Opportunity (NOFO) is to support educational activities in the mission areas of NINDS. The overarching goal of this R25 is to attract investigators who are new to or with limited exposure to clinical research, promote training of this workforce with the long-term goal of increasing the reliability and effectiveness of clinical trials by 1) introducing the principles of good clinical practice to investigators in any clinical neuroscience subspecialty, thereby providing a foundation for scientifically rigorous and ethical performance of patient oriented clinical research 2) exposing early career clinical scientists to the challenges and potential solutions to overcome these challenges in clinical research and, 3) increasing the number and expertise of knowledgeable clinical research investigators in the workforce to enhance the pipeline of scientifically sound, well-designed clinical trials. Long term, the development of well-trained, experienced clinical researchers with expertise will foster better clinical trials design and thereby hasten the introduction of improved regimens for therapy and prevention of neurological disorders into everyday medical practice and patient care.

To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on:

Courses for Skills Development: The goal of this activity is to support a clinical trial methodology course to train a group of talented, dedicated clinical neuroscience researchers to enable them to obtain external funding in the future. Key components of the course include a program of didactic lectures, individual or group projects, discussion sessions, and mentoring sessions.  The award will provide support for expenses for the implementation of the course in each year, including travel for all non-government course participants (faculty, advisors, and scholars) and all necessary materials and facilities, including meeting space, computer access, virtual meeting platform and course materials.

Research Experiences: An emphasis on early phase (i.e., phase I /II or pilot) trials within the mission areas of NINDS is essential, including pediatrics and rare diseases to address the full spectrum of neurological disorders. Developing trial designs for early phase trials are especially challenging yet critical to inform future scientific steps.  A major component of the educational course is expected to be small group protocol development sessions and individual one-on-one mentoring sessions with faculty, as well as outreach/engagement in the community to learn crucial aspects of trial development and potential recruitment. At the conclusion of the course, participant scholars should have developed a sound clinically relevant and feasible clinical trial protocol.

This NOFO aims to provide support for research education projects focused on clinical trial methodology in neurological disorders that are novel, innovative and designed to accomplish a specific goal based on a well-conceived evaluation plan. Applications will be expected to include a detailed plan to evaluate the effectiveness of the activities proposed and to include a plan for disseminating results of this program.

Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving Federal support. R25 programs may augment institutional research training programs (e.g., T32, T90) but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.

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Only one application per institution is allowed.

The purpose of this Notice of Funding Opportunity (NOFO) is to establish a Coordinating and Data Management Center (CDMC) that will coordinate and manage the activities of the Gastroenterology Neurology Research Centers (GNRCs), as described in the companion NOFO, RFA-DK-22-036, as part of the Gut Brain Parkinson's Disease Consortium (GBPDC). The responsibilities of the CDMC include, but are not limited to: (1) development of study protocols and coordination of enrollment of subjects into the study; (2) management of consortium-wide meetings and conferences, and cross-consortium collaborative activities; (3) provision of statistical and computational analysis support; and (4) establishing a central data hub for data capture, curation and management, and protocol development and registration. The CDMC will manage GBPDC-wide reporting and data and specimen sharing requirements, to include coordination of distribution of blood, biopsies, and other biological samples to the GNRCs. The CDMC will also manage the operations of the GBPDC Steering Committee and other operational committees and provide the infrastructure for the efficient design and conduct of multicenter studies and establish a repository of participant samples that may be used for ancillary studies of etiology and pathogenesis. NIDDK encourages applications from institutions that foster a diverse research environment, (for more information, see, e.g., NOT-OD-20-031), and encourages Research on Sex/Gender Differences, Sexual and Gender Minority-Related Research and Race/Ethnic Diversity (see NOT-DK-22-003). 

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Only one application per institution is allowed.

The NEI Center Core Grant combines three or more Resource and/or Service Cores for a group of R01 investigators to enhance their research, consolidate resources, avoid duplication of efforts, and/or contribute to cost effectiveness by providing a service with lower costs or higher quality than could be attempted for independent projects by several individual Program Directors/Principal Investigators (PD(s)/PI(s)). Shared resources and facilities that are accessible to a group of independently funded investigators lead to greater productivity for the separate projects and can provide instrumentation and facilities that are too costly to be maintained by an individual investigator. The design and purpose of each Center Core may vary in how it serves its users. This program is designed to enhance an institution's environment and capability to conduct vision research and to facilitate collaborative studies of the visual system and its disorders and promote new research within the NEI mission and Strategic Plan. 

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Only one application per institution is allowed.

The purpose of this notice of funding opportunity is to invite Institutional Network Awards (U2C-TL1) to cultivate a highly integrated cohort of trainees and early career investigators and to develop career development resources to accelerate kidney, urologic, and hematologic research. To maximize integration and promote a true trainee community, Institutions are invited to submit a single, unified U2C-TL1 application to engage, recruit, prepare, and sustain the next generation of scientists able to contribute to advancing research in kidney, urology, and hematology. Applications representing multiple institutions within a single metropolitan area are strongly encouraged (see Section III.3). Successful awardees are expected to relinquish all active T32s supported by the NIDDK, Division of Kidney, Urologic, and Hematologic Diseases (KUH) at the time of the U2C-TL1 award. 

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Only one application per institution is allowed.

NIOSH is seeking applications from qualified organizations for a National Center for Construction Safety and Health Research and Translation (also known as the NIOSH National Construction Center). Applicants areexpected to propose multi-disciplinary approaches for impactful applied and intervention research and hazard identification and controls, to develop partnerships for implementing prevention and intervention activities, and to serve as leaders in research translation and research-to-practice for the protection of construction workers in the United States. The NIOSH National Construction Center will accomplish these goals by 1) integrating and advancing research, 2) translating and disseminating best practices, 3) disseminating information, 4) informing policy, and 5) building capacity. Applicants must describe the occupational health and safety burden(s) addressed in their proposals. In addition, they must link the need for the proposed research and related activities to the planned outputs and outcomes that will help address or alleviate the construction sector burdens described. Applicants should also describe the anticipated impacts and potential outcomes of the proposed research and related activities that will occur during the 5-year project period and beyond.

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This Funding Opportunity Announcement (FOA) is a program within the NIH Blueprint for Neuroscience Research in conjunction with the National Institute of General Medical Sciences (NIGMS) and the National Institute on Deafness and other Communication Disorders (NIDCD).

Program Objective

The purpose of the Jointly Sponsored Predoctoral Training Program in the Neurosciences (JSPTPN) program is to provide strong, broad-based neuroscience training that will  develop a cohort of well-trained   researchers at a time when the field is advancing at a rapid pace. Neuroscience research increasingly requires investigators who can cross boundaries, draw on knowledge and interdisciplinary approaches and levels of analysis, and apply this breadth of knowledge in original ways to yield new discoveries about the function of the nervous system.

Broad-based research training. The JSPTPN supports programs of broad-based education and research experience during the first two years of graduate training. As such, training programs supported by a JSPTPN training grant must have a comprehensive, two-year training plan. During this training period, students should obtain a working knowledge of the different kinds of approaches and techniques that make up the field of neuroscience. A key component of this training should be acquiring a strong foundation of experimental methodology (e.g. experimental design, quantitative data analysis and interpretation) and a robust development of professional skills (e.g. written and oral communication and data presentation).

Core Knowledge Expectations. JSPTPN Programs should define the core knowledge that each student is expected to gain. Programs must have a clear comprehensive plan that will ensure that each student will have the tools and research experience necessary for a future career as an independent investigator in areas directly related to biomedical research in neuroscience. Each program is expected to define the core knowledge and research experience expected of all trainees. However, programs may provide a specific tailored curricula based on individual trainee background and needs.

Trainees are expected to participate in a curriculum that incorporates education in multiple levels of analysis, which may include genetics, molecular, cellular, system, behavioral and/or computational approaches. Trainees should also gain an understanding of the tools, technologies, and methods used in contemporary neuroscience research. Note that not all programs will necessarily need to cover all levels of analysis and types of technologies. However, there must be enough coverage to be considered adequate for a broad understanding of neurobiological function and the current tools used for research in neuroscience. Breadth may be achieved through any combination of formal courses, laboratory rotations, workshops and other programmatic activities. Regardless of their individual curricular plans, all students are expected to gain a general understanding of the neurobiological basis underlying diseases and disorders of the nervous system. Trainees are expected to leave the JSPTPN programs with the fundamental knowledge and skills that will allow them to lead, and confidently adapt to the rapidly growing and technologically changing field of neuroscience research.

Laboratory Rotations. Programs are expected to include laboratory rotations that allow students to explore different research areas, scientific approaches, and laboratory cultures. Rotations should have specific purpose and goals and should be designed to provide trainees with a practical understanding of the tools and experimental approaches that drive the research in the rotation laboratory. Rotations should be of sufficient duration to generate a product that results from the scientific and technological knowledge gained in the rotation laboratory.

Experimental design and statistical methodology

Experimental Design. Programs are expected to provide formal instruction in the principles of rigorous experimental design to ensure that trainees understand the practices required for robust and unbiased experimental design, hypothesis testing and the application of these principles and practices to their individual research.

Statistical Methodology. Programs should equip students with a solid understanding of statistical methodology relevant to contemporary neuroscience research and provide exposure to quantitative approaches used for a variety of experimental systems. The goals of this training are to educate trainees in 1) the importance of considering statistical principles in the design of their research, 2) the need for appropriate use of statistics in analyzing data, interpreting results and forming conclusions and 3) the practical application of statistics to date in different experimental paradigms.

Ideally, trainees will begin to develop a depth and breadth of statistical understanding that will enable them to adapt and appropriately apply statistical approaches as their experimental repertoire changes. Programs must ensure that all trainees have a solid understanding of the value and proper use of statistics, including an understanding of the many types of scientific failures that can occur due to inappropriate application of statistical tests. An introductory course in statistics is not sufficient to achieve these goals.

Quantitative Literacy and the Use of Quantitative Approaches

Quantitative Literacy. JSPTPN programs are expected to provide the background necessary for the development of quantitative skills and literacy needed to conduct rigorous research. Programmatic activities should instill an appreciation of the benefits of quantitative approaches to experimentation (and the potential pitfalls associated with a lack of quantitative consideration of their scientific system). An important specific goal of these programs is to foster the incorporation of quantitative thinking into the trainees’ research experience throughout their careers. To that end, the training activities provided by the program should equip trainees with the tools and knowledge required to examine their experimental systems quantitatively.

Quantitative Tools and Approaches. Programs are expected to provide experience in the use of practical tools for quantitative exploration, interpretation, and evaluation of biological data relevant to neuroscience research. Training in quantitative tools and approaches should be integrated into the program and reinforced during the students’ graduate careers. Ideally, training will be ongoing and progressive, with proactive approaches in place to encourage the application of quantitative thinking in the trainees’ dissertation research. For example, a program may wish to cover general principles early in the training and incorporate quantitative approaches that are directly applicable to each trainee’s research topic as they advance.

Scientific rigor. Trainees should have a thorough understanding of the principles and practices of rigorous scientific research. These principles should be examined in the context of the collection, appropriate analysis and interpretation of scientific data. Programs are also encouraged to provide education in human decision-making tendencies and cognitive biases, and how they can lead to erroneous interpretation of data (c.f. Kahneman, D. 2011. Thinking, Fast and Slow. New York. Farrar, Straus and Giroux).

Professional Skills. Regardless of career choice, an individual’s impact and success in science depends heavily on the ability to clearly articulate ideas and results in a variety of settings and to a variety of audiences. Programs are expected to provide students with strong training in professional skills such as written and oral communication. Programs should also provide training in the skills necessary for grant applications, such as grant writing, understanding the grant submission and review process, as well as understanding and addressing critiques. When appropriate, programs should encourage students to apply for individual support, such as fellowships and other individual awards from federal and non-federal sources. 

Understanding Career Opportunities.  Training programs should provide trainees access to structured career development advising and learning opportunities (e.g., workshops, discussions, and exposure to invited speakers from various career paths). Through such opportunities, trainees should obtain a general working knowledge of a variety of potential career options that would allow them to use the skills learned during their training, as well as the steps required to successfully transition to the next stage of their chosen career path.

Oversight of trainee mentoring and progression. In addition to outstanding scientific training, solid mentoring and regular career guidance are critical for advancement and success of science. Consequently, graduate programs supported by the JSPTPN are expected to have a formal oversight plan to ensure that students who obtain a Ph.D. degree do so in a timely manner, and with 1) a publication record that will allow them to progress to outstanding research opportunities, 2) written and oral presentation skills that facilitate their ability to publish their results, submit competitive grant applications , speak at national meetings to present their results, and interview for future positions, 3) an understanding of the many career opportunities available to them as Ph.D. scientists and what is required for them to compete for these different career opportunities.

This wide range of skills and knowledge needed for success in a scientific endeavor cannot be gained by students entirely within the first two years of graduate school but can be achieved with ongoing training and mentoring throughout their graduate school careers. The longitudinal oversight process designed to ensure appropriate student progress is a critical aspect of the environment in which the JSPTPN operates. Although the JSPTPN is not responsible for providing guidance beyond graduate year two, a strong JSPTPN program can only exist in an environment that is dedicated to the long-term success of its students.

Enhancing workforce diversity. NIH’s ability to help ensure that the nation remains a global leader in scientific discovery and innovation is dependent upon a pool of highly talented scientists from diverse backgrounds who will help to further NIH's mission.  See, NOT-OD-20-031. The research enterprise will be strongest when it involves individuals from a wide variety of backgrounds, who may bring new and innovative perspectives to solve the mysteries of brain function, identify the mechanisms that underlie disease and disorders and develop novel approaches to clinical treatment. Within the framework of this program’s longstanding commitment to excellence, T32-funded programs play a critical role in training individuals from diverse backgrounds, including those underrepresented in biomedical sciences.  To help address all of these critical needs, JSPTPN programs are expected to recruit students from a wide variety  of backgrounds and foster their successful completion of the graduate program and transition to their next position.

Training programs are expected to implement robust plans to enhance diversity and to promote inclusive research environments (i.e. institutional and departmental environments in which trainees from all backgrounds feel represented and integrated in the community). 

Exposure to a variety of role models. To enhance diversity, it is essential that trainees have exposure and access to a variety of role models.  Programs should actively strive to recruit prospective individuals for  program leadership, participating faculty and mentors, as well as invited speakers with varying backgrounds, perspectives, and experiences.This may include women, senior faculty who have the benefit of long experience, and junior faculty who have more recent experience in transitioning from training to independent positions.

Training Program Evaluation. Is it expected that JSPTPN programs will undergo both internal, as well as external evaluation in order to promote innovation and evolution, as well as to bring attention to any deficiencies that may arise.

Expectations for Training Program Outcomes. Trainees should leave the T32 training program with the appropriate accomplishments and skills to move on to the next step of an independent research (or research related) career pathway. Outcomes expected of training programs include strong trainee publications and other accomplishments appropriate to their training.

Special Note: Consultation with the Chair of the JSPTPN steering committee prior to application preparation is encouraged (see JSPTPN homepage).