NOT-AI-20-065: Availability of Emergency Awards for Limited Clinical Trials to Evaluate Therapeutic and Vaccine Candidates Against SARS-CoV-2

This Notice of Special Interest encourages cooperative agreement applications for implementation of investigator-initiated high-risk clinical trials, as defined by NIAID in PAR-18-633 and NOT-AI-16-084, that will augment ongoing and planned clinical trials of therapeutic and vaccine candidates directed against SARS-CoV-2 to evaluate:

NOT-MD-20-025: Simulation Modeling and Systems Science to Address Health Disparities

Support investigative and collaborative research focused on developing and evaluating simulation modeling and systems science (SMSS) to understand and address minority health and health disparities. Use SMSS to:
•Foster trans-disciplinary partnerships and collaborations in understanding the etiology and causal pathways of health disparities
•Identify modifiable barriers and cost-effective factors to reduce and eventually eliminate health disparities
•Improve patient safety and reduce medical errors for populations affected by health disparities

Emergency Awards: RADx-RAD Multimodal COVID-19 surveillance methods for high risk clustered populations (R01 Clinical Trial Optional)

NIH is issuing this Funding Opportunity Announcement (FOA) in response to the declared public health emergency issued by the Secretary, HHS, for 2019 Novel Coronavirus (COVID-19). This emergency FOA provides an expedited funding mechanism as part of the Rapid Acceleration of Diagnostics-Radical (RADx-rad) initiative.