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The CCR Grants have fostered promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. The Foundation is especially interested in hypothesis-driven studies that target breast cancer, in the development of strategies for earlier diagnosis, reduce risk of breast cancer, or increase the effectiveness of current therapies to lead to longer and better-quality outcomes for patients.  They may be considered basic, translational, clinical and/or population science. 

Award: Up to $150,000 per year (combined direct and indirect costs) for up to three years ($450,000).

Eligibility:

• Must have a doctoral degree, such as M.D., Ph.D., Dr.P.H., D.O., or equivalent.
• Must currently hold a full-time faculty appointment or have a formal offer letter from the Institution that confirms position and start date by the Application due date (October 9, 2024).
• Must not have held any faculty appointment, including non-tenure and tenure track appointments combined, for more than a total of 6 years by the Application due date.
• Must not simultaneously hold any other Grant awarded by Susan G. Komen.
• Must not currently be or have been a Principal Investigator on an existing NIH R01 grant or their equivalent as of the date of Award Notification (on or around April 15, 2025).
• Must conduct the proposed research and training at the Lead Mentor’s U.S. based institution.
• Must have adequate space and facilities to conduct the proposed research and must be able to devote at least 75% of full-time effort to breast cancer research and activities.

*The University of Arizona Cancer Center (UACC) can nominate up to two applicants but only if at least one of the two nominees identifies as as someone from groups shown to be historically minoritized and marginalized in biomedical research from National Science Foundation data (details outlined in RFA).

For more information please contact UACC-preaward@arizona.edu

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This grant mechanism aims to help outstanding senior postdoctoral fellows and clinical fellows, working under the guidance of a mentor, launch their competitive, independent breast cancer research careers. Career Transition Awards provide up to five years of funding in two phases: Phase 1 supports the final years of mentored, postdoctoral training; and Phase 2 supports the independent research of the early career, tenure-track investigators. 

Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science. 

Komen’s research priorities are conquering metastatic and aggressive breast cancers, advancing personalized breast cancer care throughout the continuum of care and eliminating breast cancer disparities and inequities. 

Eligibility:

• Individuals pursuing independent breast cancer research careers who are in the final years of mentored postdoctoral research training positions with no more than five years of total postdoctoral research experience at the time of Letter of Intent submission (August 7, 2024). For this application clinical fellows are considered eligible and equal to the postdoctoral rank.
• Must have a doctoral degree, including M.D., Ph.D., Dr.P.H., D.O., or equivalent.
• May not hold any appointment designated as faculty (e.g., assistant professor, clinical assistant professor, faculty-level instructor, or equivalent). Clinical fellows with the title instructor are allowed as long as they are no more than 5 years into their training similar to above bullet concerning postdoctoral training.
• Must be able to devote at least 75% of full-time effort to breast cancer research and activities, i.e., protected research time.
• Applicant/PI may not hold another career transition award, training award (K-type awards) or R-type award at time of notification of intent to fund (on or around April 15, 2025). If Applicant previously held an R-type award at any point, they are not eligible to apply for this award.
• Is not required to be a U.S. citizen or permanent resident.

*The University of Arizona Cancer Center (UACC) can nominate up to two applicants but only if at least one of the two nominees identifies as as someone from groups shown to be historically minoritized and marginalized in biomedical research from National Science Foundation data (details outlined in RFA).

For more information please contact UACC-preaward@arizona.edu

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HRSA will only review your first validated application under HRSA-25-085 in Grants.gov.

This Notice of Funding Opportunity (NOFO) announces the opportunity to apply for New Access Points (NAP) funding under the Health Center Program. The purpose of this funding is to support new health center service delivery sites to expand affordable, accessible, and high-quality primary health care for underserved communities and populations. In this NOFO, such sites are referred to as new access points. Award recipients will use NAP funding to provide primary health care services at one or more new access points

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*Applicant institutions are  limited to three pre-applications and three applications for each program (ASCR, BES, BER, FES, HEP, NP, DOE IP, ARDAP).

The Office of Science (SC) seeks applications for fundamental research in fields supported by SC to build research capacity at institutions historically underrepresented in the SC portfolio, i.e. non-R1 minority serving institutions (MSIs) and non-R1 emerging research institutions (ERIs). This FOA aims to build research capacity, including infrastructure and expertise at these institutions, through mutually beneficial relationships between applicants and DOE national laboratories, SC scientific user facilities, or R1 MSI/ERIs. 

SC supports fundamental research in applied mathematics, biology, chemistry, computer science, engineering, geoscience, isotope research, materials science, fusion energy science, and physics to transform our understanding of nature and catalyze scientific discoveries that can lead to technical breakthroughs. All applications to SC should focus on hypothesis-driven basic research. SC does not support applied research, product development, or prototyping.

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HRSA will only review your last validated application before the Grants.gov due date.

This program will fund one entity to provide data support to rural maternal health care networks to assist efforts to improve maternal health care at the community- and regional-levels. This program will also fund the use of data to inform the improvement of rural maternal health care nationwide.

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Applicant institutions are limited to no more than four (4) pre-applications or applications as a lead institution and no more than one pre-application or application for any individual PI.

The Department of Energy (DOE) Fusion Energy Science (FES) program is embarking on a transformative initiative aimed at creating a fusion innovation ecosystem, the “Fusion Innovation Research Engine (FIRE)”, by forming virtual, centrally managed teams called “Collaboratives”, that have a collective goal of bridging FES’s basic science research programs and growing fusion industries, including the activities supported under the FES milestone-based fusion development program.

At its core, FIRE represents a departure from traditional science programs. It is structured as a framework comprised of Collaboratives with the purpose of bridging the gap between foundational science and practical application. These Collaboratives are envisioned as dynamic hubs of innovation, driving advancements in fusion energy research in collaboration with both public and private entities. FES envisions the ecosystem surrounding the Collaboratives as a facilitator for collaboration and coordination with the basic science research program and other stakeholders, creating an engine for innovation. FIRE hopes to foster synergy and alignment of goals, accelerating progress towards the realization of fusion energy as a clean, sustainable power source. Moreover, this initiative aims to create new economic opportunities, bolster US-based manufacturing and supply chains, and enable the development of technologies crucial for national security, energy security, and defense.

FES envisions FIRE Collaboratives as a collection of virtual, centrally managed teams. These teams leverage expertise, capabilities, and facilities to systematically address FS&T gaps, fostering integrated research efforts, facilitating collaboration among diverse stakeholders, and enhancing communication to accelerate progress in enabling fusion energy. The term ‘fusion ecosystem’ refers to the network of collaborative relationships, resources, and initiatives aimed at advancing fusion energy. Within this ecosystem, FIRE Collaboratives serve as a pivotal component, driving coordinated efforts to address key challenges and accelerate advancements in fusion science and technology.

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Only one application per institution is allowed. 

The purpose of this notice of funding opportunity is to invite Institutional Network Awards (U2C-TL1) to cultivate a highly integrated cohort of trainees and early career investigators and to develop career development resources to accelerate kidney, urologic, and hematologic research. To maximize integration and promote a true trainee community, Institutions are invited to submit a single, unified U2C-TL1 application to engage, recruit, prepare, and sustain the next generation of scientists able to contribute to advancing research in kidney, urology, and hematology. Applications representing multiple institutions within a single metropolitan area are strongly encouraged (see Section III.3). Successful awardees are expected to relinquish all active T32s supported by the NIDDK, Division of Kidney, Urologic, and Hematologic Diseases (KUH) at the time of the U2C-TL1 award.

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Only one application per institution is allowed.

This Funding Opportunity Announcement (FOA) invites applications from institutions proposing to establish, or renew, an Alzheimer's Disease Research Center (ADRC).

NIA-designated ADRCs serve as a national resource for research on the nature of Alzheimer’s disease (AD) and AD-related dementias (ADRD) and the development of more effective approaches to prevention, diagnosis, care, and therapy. They create shared resources that support dementia-relevant research, and they collaborate and coordinate their research efforts with other NIH-funded programs and investigators. 

Applications may request a budget of up to $2.925 million in direct costs per year.

The maximum project period is 5 years.

Areas of Interest

The objective of NIA's ADRC Program is to foster highly interactive, cutting-edge AD/ADRD research through core services that seek to accomplish the following:

• Create an environment that supports innovative multidisciplinary, inclusive research that has a significant impact on the field of dementia research and treatment;
• Foster interdisciplinary collaborations, especially in emerging areas of research, to catalyze new ideas and scientific approaches;
• Attract, educate and/or train, and retain a group of early stage investigators and investigators new to dementia research that is richly diverse in backgrounds, and academic and technical disciplines;
• Translate scientific discoveries from bench to bedside to community that improve public health and include validation and effectiveness measures;
• Provide rapid and broad sharing of analytic and research tools, as well as data, as appropriate and as consistent with achieving the goals of the program; and
• Enhance dementia-related research education opportunities for people living with dementia, their care partners, students, scientists, and clinicians.

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Only one application per institution is allowed.

This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK.  The purpose of this Centers program is to bring together basic and clinical investigators as a means to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission.  DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner.  Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding. 

This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material.

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Only two applications per institution (normally identified by having a Unique Entity Identifier (UEI) number or NIH IPF number) are allowed.

The NIH Director's Early Independence Award supports rigorous and promising investigators who wish to pursue independent research soon after completion of their terminal doctoral degree or post-graduate clinical training, thereby forgoing the traditional post-doctoral training period and accelerating their entry into an independent research career. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIH’s Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director's Early Independence Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

Requirements:

• Single PD/PI: Only single PD/PI applications are allowed. Multiple PD/PIs applications will not be accepted. Only the PD/PI may be listed as a Senior/Key Person and provide a Biographical Sketch.
• Citizenship: U.S. citizenship is not required. For non-U.S. citizens, the applicant institution is responsible for ensuring the PD/PI's U.S. visa status will allow them to conduct the proposed research at the applicant institution for the entire project period.
• Degree Receipt Date: The receipt date of the PD/PI’s terminal doctoral degree or end of post-graduate clinical training must be between May 1, 2023, and September 30, 2025. The degree receipt date is that which appears on the official transcript for the degree. The end of post-graduate clinical training includes residency and fellowship periods. At the time of award, either:

1. The PD/PI must have received a PhD, MD, DO, DC, DDS, DVM, OD, DPM, ScD, EngD, DrPH, DNSc, ND (Doctor of Naturopathy), PharmD, DSW, PsyD, or equivalent doctoral degree from an accredited domestic or foreign institution (it is the responsibility of the sponsoring institution to determine if a foreign doctoral degree is equivalent).
2. Or an authorized official of the degree-granting or training institution must certify that all degree requirements have been met and that the receipt date of the degree (as will appear on the transcript) will be before September 30, 2025. An authorized official of the host institution must certify that the PD/PI will be able to conduct independent research at the institution at the time of the project start date.

• Post-doctoral Experience: The PD/PI must not have served as a post-doctoral fellow for more than 12 months following a previous, non-terminal doctoral degree (this only applies to PD/PIs with multiple doctoral degrees who served in a 12+ month post-doctoral fellowship before their terminal degree).
• Level of Effort: In the first and second years of the project period, the PD/PI must commit at least 9.6 person-months of effort to the Early Independence Award project each year (80% effort per year). In years 3-5 of the project period, the PD/PI may reduce their effort on the Early Independence Award project but must still conduct at least 9.6 person-months of general independent research each year (80% effort per year). General independent research includes the effort spent on the Early Independence Award project and any other independent research projects the PD/PI is working on.
• Non-independence at Time of Application: Individuals are eligible only if they do not have research independence at the time of application submission. Research non-independence is defined functionally rather than by position title and must have all the following characteristics:
  1. The PD/PI's current research agenda is set through concurrence with mentors.
  2. The PD/PI's research is funded primarily through support to other investigators (mentored fellowships such as NIH F31 or F32 Fellowships or NSF Graduate Research Fellowships do not preclude eligibility).
  3. The PD/PI does not have any space assigned directly by the institution for the conduct of their research.
  4. The PD/PI cannot apply for an NIH R01 grant without a special waiver or exemption from the institution according to institutional policy.

Though PD/PIs must not be functionally independent at the time of application submission, they may become functionally independent prior to time of award and still retain eligibility.

• Independent Research Position: An independent research position at a host institution is required, and the PD/PI must be able to begin independent research by the project start date. The position need not be permanent or tenure-track and may be contingent upon receipt of the Early Independence Award. Prospective PD/PIs should contact appropriate institutional leaders to seek an appointment to an independent research position. Alternatively, institutions may actively recruit eligible scientists to apply for support through this initiative. In either case, the institution is expected to provide substantial support to the PD/PI as detailed in the Facilities & Other Resources section. To foster independence, PD/PIs may benefit from being hosted by an institution at which they have not previously studied or trained.
• Career Awards: PD/PIs may apply for a research career development (K) award and DP5 at the same time, but NIH policy prohibits scientific overlap. A PD/PI may not hold a DP5 and career development award concurrently: The career development award must be relinquished to receive the DP5.
• Site Visit: NIH staff will conduct a one-time site visit at the end of the first year to assess the PD/PI's progress and to ensure they are receiving the institutional resources and support outlined in the application. NIH staff will meet with the PD/PI, lab personnel, mentors, faculty, and institutional leadership. Failure to provide independence and/or support may lead to NIH actions, including reduction of funds.

Awards will be for up to $250,000 in direct costs per year, plus applicable Facilities and Administrative (F&A) costs.